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Pandora's Box is an item unlocked by beating Dark Room with Lazarus. It can be found in Shops and Red Chests, and it's a one-time use spacebar item. Pandora's Box will give you a certain set of items depending on the floor you're using it. Then, how do you unlock Pandora's box? "On consoles (Switch, PS4), Moving Box is unlocked by opening Pandora's Box in the Chest, not in the Dark Room, where it does not do anything." Is this true? how do you get to the void binding of Isaac? Access. The Void is unlocked by defeating Hush. After defeating Hush at least once, a new exit will appear in the upper right-hand corner of the 2x2 boss room in which Hush was fought. In this way, how do you unlock the dark room? To get to the Dark Room , you must first beat Satan in Sheol, 5 times unlocking the Negative. When you beat mom she drops the Negative. when you beat moms heart go down into Shoel, beat Satan, walk into the chest and be taken to the dark ...